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Research Article

Cell-Passage Activity Is Required for the Malarial Parasite to Cross the Liver Sinusoidal Cell Layer

  • Tomoko Ishino,

    Affiliation: Mie University School of Medicine, Mie, Japan

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  • Kazuhiko Yano,

    Affiliation: Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

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  • Yasuo Chinzei,

    Affiliations: Mie University School of Medicine, Mie, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

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  • Masao Yuda mail

    To whom correspondence should be addressed. E-mail: m-yuda@doc.medic.mie-u.ac.jp

    Affiliations: Mie University School of Medicine, Mie, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

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  • Published: January 20, 2004
  • DOI: 10.1371/journal.pbio.0020004

About the Authors

Tomoko Ishino, Yasuo Chinzei, Masao Yuda
Mie University School of Medicine, Mie, Japan
Kazuhiko Yano, Yasuo Chinzei, Masao Yuda
Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

Corresponding Author

Email: m-yuda@doc.medic.mie-u.ac.jp

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

TI, YC, and MY conceived and designed the experiments. TI, KY, and MY performed the experiments. TI and MY analyzed the data. TI and MY wrote the paper.