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Research Article

Fusion of Protein Aggregates Facilitates Asymmetric Damage Segregation

  • Miguel Coelho equal contributor,

    equal contributor Contributed equally to this work with: Miguel Coelho, Steven J. Lade

    Affiliations: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Steven J. Lade equal contributor,

    equal contributor Contributed equally to this work with: Miguel Coelho, Steven J. Lade

    Affiliations: Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, Stockholm Resilience Centre, Stockholm University, Stockholm, Sweden

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  • Simon Alberti,

    Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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  • Thilo Gross,

    Affiliations: Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, Department of Engineering Mathematics, Merchant Venturers School of Engineering, University of Bristol, Bristol, United Kingdom

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  • Iva M. Tolić mail

    tolic@mpi-cbg.de or tolic@irb.hr

    Affiliations: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia

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  • Published: June 17, 2014
  • DOI: 10.1371/journal.pbio.1001886

About the Authors

Miguel Coelho, Simon Alberti, Iva M. Tolić
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Miguel Coelho
FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America
Steven J. Lade, Thilo Gross
Max Planck Institute for the Physics of Complex Systems, Dresden, Germany
Steven J. Lade
Stockholm Resilience Centre, Stockholm University, Stockholm, Sweden
Thilo Gross
Department of Engineering Mathematics, Merchant Venturers School of Engineering, University of Bristol, Bristol, United Kingdom
Iva M. Tolić
Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia

Corresponding Author

Email: tolic@mpi-cbg.de or tolic@irb.hr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MC SL SA IT. Performed the experiments: MC SL. Analyzed the data: MC SL SA TG IT. Contributed reagents/materials/analysis tools: MC SL SA TG IT. Wrote the paper: MC SL SA TG IT. Have an equal contribution as first authors: MC SL.