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Research Article

Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11

  • Wu-Lin Charng,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Shinya Yamamoto,

    Affiliations: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Jan and Dan Duncan Neurological Research Institute, Texas Children′s Hospital, Houston, Texas, United States of America

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  • Manish Jaiswal,

    Affiliations: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America

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  • Vafa Bayat,

    Affiliations: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas, United States of America

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  • Bo Xiong,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Ke Zhang,

    Affiliation: Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Hector Sandoval,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Gabriela David,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Stephen Gibbs,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Hsiang-Chih Lu,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Kuchuan Chen,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Nikos Giagtzoglou,

    Affiliations: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Neurology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Hugo J. Bellen mail

    hbellen@bcm.edu

    Affiliations: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Jan and Dan Duncan Neurological Research Institute, Texas Children′s Hospital, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America, Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America

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  • Published: January 28, 2014
  • DOI: 10.1371/journal.pbio.1001777

About the Authors

Wu-Lin Charng, Shinya Yamamoto, Vafa Bayat, Bo Xiong, Gabriela David, Hsiang-Chih Lu, Kuchuan Chen, Hugo J. Bellen
Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America
Shinya Yamamoto, Manish Jaiswal, Hector Sandoval, Stephen Gibbs, Nikos Giagtzoglou, Hugo J. Bellen
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
Shinya Yamamoto, Hugo J. Bellen
Jan and Dan Duncan Neurological Research Institute, Texas Children′s Hospital, Houston, Texas, United States of America
Manish Jaiswal, Hugo J. Bellen
Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America
Vafa Bayat
Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas, United States of America
Ke Zhang, Hugo J. Bellen
Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
Nikos Giagtzoglou
Department of Neurology, Baylor College of Medicine, Houston, Texas, United States of America
Hugo J. Bellen
Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Author

Email: hbellen@bcm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: WLC SY HJB. Performed the experiments: WLC SY MJ BX KZ HS GD SG HCL KC NG VB. Analyzed the data: WLC HJB. Contributed reagents/materials/analysis tools: SY KC NG. Wrote the paper: WLC HJB.