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Research Article

Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

  • Ariel E. Mechaly,

    Affiliation: Institut Pasteur, Unité de Microbiologie Structurale and CNRS UMR 3528, Paris, France

    Current address: Unit of Protein Crystallography, Institut Pasteur de Montevideo, Montevideo, Uruguay.

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  • Nathalie Sassoon,

    Affiliation: Institut Pasteur, Unité de Microbiologie Structurale and CNRS UMR 3528, Paris, France

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  • Jean-Michel Betton,

    Affiliation: Institut Pasteur, Unité de Microbiologie Structurale and CNRS UMR 3528, Paris, France

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  • Pedro M. Alzari mail

    pedro.alzari@pasteur.fr

    Affiliation: Institut Pasteur, Unité de Microbiologie Structurale and CNRS UMR 3528, Paris, France

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  • Published: January 28, 2014
  • DOI: 10.1371/journal.pbio.1001776

About the Authors

Ariel E. Mechaly, Nathalie Sassoon, Jean-Michel Betton, Pedro M. Alzari
Institut Pasteur, Unité de Microbiologie Structurale and CNRS UMR 3528, Paris, France

Corresponding Author

Email: pedro.alzari@pasteur.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: AEM JMB PMA. Performed the experiments: AEM NS JMB. Analyzed the data: AEM NS JMB PMA. Wrote the paper: AEM JMB PMA.