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Research Article

Mechanism of Membranous Tunnelling Nanotube Formation in Viral Genome Delivery

  • Bibiana Peralta,

    Affiliation: Structural Biology Unit, CIC bioGUNE, CIBERehd, Derio, Spain

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  • David Gil-Carton,

    Affiliation: Structural Biology Unit, CIC bioGUNE, CIBERehd, Derio, Spain

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  • Daniel Castaño-Díez,

    Affiliation: Center for Cellular Imaging and Nano-Analitics (C-CINA) Biozentrum, University of Basel, Basel, Switzerland

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  • Aurelie Bertin,

    Affiliation: Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université de Paris–Sud, Orsay, France

    Current address: Institut Curie, UMR CNRS 168, Paris, France.

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  • Claire Boulogne,

    Affiliation: Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université de Paris–Sud, Orsay, France

    Current address: Imagif Facility, Microscopie Electronique, Gif-sur-Yvette, France.

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  • Hanna M. Oksanen,

    Affiliation: Institute of Biotechnology and Department of Biosciences, Viikki Biocenter, University of Helsinki, Finland

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  • Dennis H. Bamford,

    Affiliation: Institute of Biotechnology and Department of Biosciences, Viikki Biocenter, University of Helsinki, Finland

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  • Nicola G. A. Abrescia mail

    nabrescia@cicbiogune.es

    Affiliations: Structural Biology Unit, CIC bioGUNE, CIBERehd, Derio, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain

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  • Published: September 24, 2013
  • DOI: 10.1371/journal.pbio.1001667

About the Authors

Bibiana Peralta, David Gil-Carton, Nicola G. A. Abrescia
Structural Biology Unit, CIC bioGUNE, CIBERehd, Derio, Spain
Daniel Castaño-Díez
Center for Cellular Imaging and Nano-Analitics (C-CINA) Biozentrum, University of Basel, Basel, Switzerland
Aurelie Bertin, Claire Boulogne
Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université de Paris–Sud, Orsay, France
Hanna M. Oksanen, Dennis H. Bamford
Institute of Biotechnology and Department of Biosciences, Viikki Biocenter, University of Helsinki, Finland
Nicola G. A. Abrescia
IKERBASQUE, Basque Foundation for Science, Bilbao, Spain

Corresponding Author

Email: nabrescia@cicbiogune.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: NGAA DHB AB DC. Performed the experiments: BP DG DC AB CB HMO NGAA. Analyzed the data: NGAA BP DG DC AB HMO DHB. Wrote the paper: NGAA DHB HMO AB DC. Conceived and designed the study: NGAA.