Advertisement
Research Article

RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins

  • Kohila Mahadevan equal contributor,

    equal contributor Contributed equally to this work with: Kohila Mahadevan, Hui Zhang

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    X
  • Hui Zhang equal contributor,

    equal contributor Contributed equally to this work with: Kohila Mahadevan, Hui Zhang

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    X
  • Abdalla Akef,

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    X
  • Xianying A. Cui,

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    X
  • Serge Gueroussov,

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    X
  • Can Cenik,

    Affiliations: Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Department of Biochemistry and Molecular Pharmacology University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Frederick P. Roth,

    Affiliations: Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

    X
  • Alexander F. Palazzo mail

    alex.palazzo@utoronto.ca

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    X
  • Published: April 23, 2013
  • DOI: 10.1371/journal.pbio.1001545

About the Authors

Kohila Mahadevan, Hui Zhang, Abdalla Akef, Xianying A. Cui, Serge Gueroussov, Alexander F. Palazzo
Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
Can Cenik, Frederick P. Roth
Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
Can Cenik
Howard Hughes Medical Institute, Department of Biochemistry and Molecular Pharmacology University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Frederick P. Roth
Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada
Frederick P. Roth
Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

Corresponding Author

Email: alex.palazzo@utoronto.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: KM HZ AFP. Performed the experiments: KM HZ AA XAC SG AFP. Analyzed the data: KM HZ AA XAC CC FPR AFP. Contributed reagents/materials/analysis tools: FPR AFP. Wrote the paper: KM HZ AFP.