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Research Article

Vascular Calcifying Progenitor Cells Possess Bidirectional Differentiation Potentials

  • Hyun-Ju Cho equal contributor,

    equal contributor Contributed equally to this work with: Hyun-Ju Cho, Hyun-Jai Cho

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Hyun-Jai Cho equal contributor,

    equal contributor Contributed equally to this work with: Hyun-Ju Cho, Hyun-Jai Cho

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Ho-Jae Lee,

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Myung-Kang Song,

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Ji-Yun Seo,

    Affiliation: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea

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  • Yeon-Hee Bae,

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Ju-Young Kim,

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Hae-Young Lee,

    Affiliation: Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

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  • Whal Lee,

    Affiliation: Department of Radiology, Seoul National University College of Medicine, Seoul, Korea

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  • Bon-Kwon Koo,

    Affiliation: Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

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  • Byung-Hee Oh,

    Affiliation: Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

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  • Young-Bae Park,

    Affiliations: Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea

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  • Hyo-Soo Kim mail

    hyosoo@snu.ac.kr

    Affiliations: National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea, Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea, World Class University Program, Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Korea

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  • Published: April 09, 2013
  • DOI: 10.1371/journal.pbio.1001534

About the Authors

Hyun-Ju Cho, Hyun-Jai Cho, Ho-Jae Lee, Myung-Kang Song, Ji-Yun Seo, Yeon-Hee Bae, Ju-Young Kim, Hyo-Soo Kim
National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea
Hyun-Ju Cho, Hyun-Jai Cho, Hae-Young Lee, Bon-Kwon Koo, Byung-Hee Oh, Young-Bae Park, Hyo-Soo Kim
Cardiovascular Center & Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
Hyun-Ju Cho, Hyun-Jai Cho, Ho-Jae Lee, Myung-Kang Song, Yeon-Hee Bae, Ju-Young Kim, Young-Bae Park, Hyo-Soo Kim
Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
Whal Lee
Department of Radiology, Seoul National University College of Medicine, Seoul, Korea
Hyo-Soo Kim
World Class University Program, Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Korea

Corresponding Author

Email: hyosoo@snu.ac.kr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: HJC (Hyun-Ju Cho), HJC (Hyun-Jai Cho), HSK. Performed the experiments: HJC (Hyun-Ju Cho), HJC (Hyun-Jai Cho), HJL, MKS, YHB, JYK, HYL, JYS, WL. Analyzed the data: HJC (Hyun-Ju Cho), HJC (Hyun-Jai Cho), HJL, MKS, YHB, JYS, JYK, HYL, BKK, BHO, YBP. Wrote the paper: HJC (Hyun-Ju Cho), HJC (Hyun-Jai Cho), HSK.