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Research Article

Promoter Sequence Determines the Relationship between Expression Level and Noise

  • Lucas B. Carey equal contributor,

    equal contributor Contributed equally to this work with: Lucas B. Carey, David van Dijk

    Affiliation: Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel

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  • David van Dijk equal contributor,

    equal contributor Contributed equally to this work with: Lucas B. Carey, David van Dijk

    Affiliations: Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel, Computational Science, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Peter M. A. Sloot,

    Affiliations: School of Computer Engineering, Nanyang Technological University, Singapore, Computational Science, University of Amsterdam, Amsterdam, The Netherlands

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  • Jaap A. Kaandorp,

    Affiliation: Computational Science, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Eran Segal mail

    eran.segal@weizmann.ac.il

    Affiliation: Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel

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  • Published: April 02, 2013
  • DOI: 10.1371/journal.pbio.1001528

About the Authors

Lucas B. Carey, David van Dijk, Eran Segal
Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel
Peter M. A. Sloot
School of Computer Engineering, Nanyang Technological University, Singapore
David van Dijk, Peter M. A. Sloot, Jaap A. Kaandorp
Computational Science, University of Amsterdam, Amsterdam, The Netherlands

Corresponding Author

Email: eran.segal@weizmann.ac.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: LBC DD ES. Performed the experiments: LBC DD. Analyzed the data: LBC DD. Contributed reagents/materials/analysis tools: LBC DD. Wrote the paper: LBC DD ES PS JK.