Advertisement
Research Article

The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway

  • Uma Karthika Rajarajacholan,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada

    X
  • Subhash Thalappilly,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada

    X
  • Karl Riabowol mail

    karl@ucalgary.ca

    Affiliations: Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada, Department of Oncology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

    X
  • Published: March 05, 2013
  • DOI: 10.1371/journal.pbio.1001502

About the Authors

Uma Karthika Rajarajacholan, Subhash Thalappilly, Karl Riabowol
Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada
Karl Riabowol
Department of Oncology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

Corresponding Author

Email: karl@ucalgary.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: UKR ST KR. Performed the experiments: UKR ST. Analyzed the data: UKR ST KR. Contributed reagents/materials/analysis tools: UKR ST. Wrote the paper: UKR KR.