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Research Article

The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation

  • Cheng-Hai Zhang,

    Affiliation: Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    Current address: Model Animal Research Center, Nanjing University, Nanjing, China

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  • Lawrence M. Lifshitz,

    Affiliations: Biomedical Imaging Group, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Karl F. Uy,

    Affiliation: Department of Surgery, Division of Thoracic Surgery, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, United States of America

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  • Mitsuo Ikebe,

    Affiliation: Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Kevin E. Fogarty,

    Affiliations: Biomedical Imaging Group, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Ronghua ZhuGe mail

    ronghua.zhuge@umassmed.edu

    Affiliations: Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Biomedical Imaging Group, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Published: March 05, 2013
  • DOI: 10.1371/journal.pbio.1001501

About the Authors

Cheng-Hai Zhang, Mitsuo Ikebe, Ronghua ZhuGe
Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Lawrence M. Lifshitz, Kevin E. Fogarty, Ronghua ZhuGe
Biomedical Imaging Group, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Lawrence M. Lifshitz, Kevin E. Fogarty
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Karl F. Uy
Department of Surgery, Division of Thoracic Surgery, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, United States of America

Corresponding Author

Email: ronghua.zhuge@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Edited paper: LML. Conceived and designed the experiments: RZG. Performed the experiments: CZ RZG. Analyzed the data: CZ LML KEF RZG. Contributed reagents/materials/analysis tools: KFU MI. Wrote the paper: RZG.