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Research Article

The Molecular Basis for Recognition of CD1d/α-Galactosylceramide by a Human Non-Vα24 T Cell Receptor

  • Jacinto López-Sagaseta,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America

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  • Jennifer E. Kung,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America

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  • Paul B. Savage,

    Affiliation: Department of Chemistry, Brigham Young University, Provo, Utah, United States of America

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  • Jenny Gumperz,

    Affiliation: Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

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  • Erin J. Adams mail

    ejadams@uchicago.edu

    Affiliations: Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America, Committee on Immunology, University of Chicago, Chicago, Illinois, United States of America

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  • Published: October 23, 2012
  • DOI: 10.1371/journal.pbio.1001412

About the Authors

Jacinto López-Sagaseta, Jennifer E. Kung, Erin J. Adams
Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America
Paul B. Savage
Department of Chemistry, Brigham Young University, Provo, Utah, United States of America
Jenny Gumperz
Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
Erin J. Adams
Committee on Immunology, University of Chicago, Chicago, Illinois, United States of America

Corresponding Author

Email: ejadams@uchicago.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: JLS JG EJA. Performed the experiments: JLS JEK. Analyzed the data: JLS EJA. Contributed reagents/materials/analysis tools: PBS JG. Wrote the paper: JLS EJA.