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Research Article

Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine

  • Christoph Seiler,

    Affiliation: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Gangarao Davuluri,

    Affiliation: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Joshua Abrams,

    Affiliation: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Fitzroy J. Byfield,

    Affiliation: Department of Physiology, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Paul A. Janmey,

    Affiliation: Department of Physiology, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Michael Pack mail

    mpack@mail.med.upenn.edu

    Affiliations: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Published: September 04, 2012
  • DOI: 10.1371/journal.pbio.1001386

About the Authors

Christoph Seiler, Gangarao Davuluri, Joshua Abrams, Michael Pack
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
Fitzroy J. Byfield, Paul A. Janmey
Department of Physiology, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Michael Pack
Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: mpack@mail.med.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: CS MP PJ. Performed the experiments: CS GD JA FB. Analyzed the data: CS GD JA FB PJ MP. Contributed reagents/materials/analysis tools: CS GD JA FB PJ MP. Wrote the paper: CS MP.