Advertisement
Research Article

The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Initiation of Neuronal Regeneration in Caenorhabditis elegans

  • Berangere Pinan-Lucarre equal contributor,

    equal contributor Contributed equally to this work with: Berangere Pinan-Lucarre, Christopher V. Gabel

    Affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

    Current address: Institut de Biologie de l'Ecole Normale Supérieure, Paris, France

    X
  • Christopher V. Gabel equal contributor mail,

    equal contributor Contributed equally to this work with: Berangere Pinan-Lucarre, Christopher V. Gabel

    cvgabel@bu.edu (CVG) (CG); samuel@physics.harvard.edu (AS) (AS)

    Affiliation: Department of Physics and Center for Brain Science, Harvard University, Cambridge, Massachusetts, United States of America

    Current address: Department of Physiology and Biophysics, Boston University School of Medicine, Boston University Photonics Center, Boston, Massachusetts, United States of America

    X
  • Christopher P. Reina,

    Affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

    X
  • S. Elizabeth Hulme,

    Affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Sergey S. Shevkoplyas,

    Affiliation: Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States of America

    X
  • R. Daniel Slone,

    Affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

    X
  • Jian Xue,

    Affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

    X
  • Yujie Qiao,

    Affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

    X
  • Sarah Weisberg,

    Affiliation: Department of Physics and Center for Brain Science, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Kevin Roodhouse,

    Affiliation: Department of Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Lin Sun,

    Affiliation: Department of Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts, United States of America

    X
  • George M. Whitesides,

    Affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Aravinthan Samuel mail,

    cvgabel@bu.edu (CVG) (CG); samuel@physics.harvard.edu (AS) (AS)

    Affiliation: Department of Physics and Center for Brain Science, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Monica Driscoll

    Affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

    X
  • Published: May 22, 2012
  • DOI: 10.1371/journal.pbio.1001331

About the Authors

Berangere Pinan-Lucarre, Christopher P. Reina, R. Daniel Slone, Jian Xue, Yujie Qiao, Monica Driscoll
Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America
Christopher V. Gabel, Sarah Weisberg, Aravinthan Samuel
Department of Physics and Center for Brain Science, Harvard University, Cambridge, Massachusetts, United States of America
S. Elizabeth Hulme, George M. Whitesides
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
Sergey S. Shevkoplyas
Department of Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States of America
Kevin Roodhouse, Lin Sun
Department of Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: BPL CVG CPR SHE SES GMW AS MD. Performed the experiments: BPL CVG CPR SHE SES RDS JX YQ SW KR LS. Analyzed the data: BPL CVG AS MD. Wrote the paper: BPL CVG AS MD.