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Research Article

Evolutionarily Conserved Linkage between Enzyme Fold, Flexibility, and Catalysis

  • Arvind Ramanathan,

    Affiliations: Joint CMU–Pitt Program in Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America, Computational Biology Institute, and Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

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  • Pratul K. Agarwal mail

    agarwalpk@ornl.gov

    Affiliation: Computational Biology Institute, and Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

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  • Published: November 08, 2011
  • DOI: 10.1371/journal.pbio.1001193

About the Authors

Arvind Ramanathan
Joint CMU–Pitt Program in Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
Arvind Ramanathan, Pratul K. Agarwal
Computational Biology Institute, and Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

Corresponding Author

Email: agarwalpk@ornl.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: AR PKA. Performed the experiments: AR PKA. Analyzed the data: AR PKA. Contributed reagents/materials/analysis tools: AR PKA. Wrote the paper: AR PKA.