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Research Article

Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

  • Alice C. N. Brown,

    Affiliation: Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom

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  • Stephane Oddos,

    Affiliation: Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom

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  • Ian M. Dobbie,

    Affiliation: Department of Biochemistry, University of Oxford, Oxford, United Kingdom

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  • Juha-Matti Alakoskela,

    Affiliation: Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom

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  • Richard M. Parton,

    Affiliation: Department of Biochemistry, University of Oxford, Oxford, United Kingdom

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  • Philipp Eissmann,

    Affiliation: Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom

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  • Mark A. A. Neil,

    Affiliation: Department of Physics, Imperial College London, London, United Kingdom

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  • Christopher Dunsby,

    Affiliation: Department of Physics, Imperial College London, London, United Kingdom

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  • Paul M. W. French,

    Affiliation: Department of Physics, Imperial College London, London, United Kingdom

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  • Ilan Davis,

    Affiliation: Department of Biochemistry, University of Oxford, Oxford, United Kingdom

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  • Daniel M. Davis mail

    d.davis@imperial.ac.uk

    Affiliation: Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom

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  • Published: September 13, 2011
  • DOI: 10.1371/journal.pbio.1001152

About the Authors

Alice C. N. Brown, Stephane Oddos, Juha-Matti Alakoskela, Philipp Eissmann, Daniel M. Davis
Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom
Ian M. Dobbie, Richard M. Parton, Ilan Davis
Department of Biochemistry, University of Oxford, Oxford, United Kingdom
Mark A. A. Neil, Christopher Dunsby, Paul M. W. French
Department of Physics, Imperial College London, London, United Kingdom

Corresponding Author

Email: d.davis@imperial.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: ACNB SO IMD J-MA DMD. Performed the experiments: ACNB SO IMD. Analyzed the data: ACNB SO J-MA. Contributed reagents/materials/analysis tools: J-MA PE ID. Wrote the paper: ACNB DMD. Helped establish novel instrumentation: IMD RMP MAAN CD PMWF ID.