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Modernizing Reference Genome Assemblies

  • Deanna M. Church mail,

    church@ncbi.nlm.nih.gov

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Valerie A. Schneider,

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Tina Graves,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Katherine Auger,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Fiona Cunningham,

    Affiliation: The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Nathan Bouk,

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Hsiu-Chuan Chen,

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Richa Agarwala,

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • William M. McLaren,

    Affiliation: The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Graham R.S. Ritchie,

    Affiliation: The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Derek Albracht,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Milinn Kremitzki,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Susan Rock,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Holland Kotkiewicz,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Colin Kremitzki,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Aye Wollam,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

    X
  • Lee Trani,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Lucinda Fulton,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Robert Fulton,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Lucy Matthews,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Siobhan Whitehead,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Will Chow,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • James Torrance,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

    X
  • Matthew Dunn,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Glenn Harden,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Glen Threadgold,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Jonathan Wood,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Joanna Collins,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Paul Heath,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Guy Griffiths,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Sarah Pelan,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Darren Grafham,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Evan E. Eichler,

    Affiliations: Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, United States of America, Howard Hughes Medical Institute, Seattle, Washington, United States of America

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  • George Weinstock,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Elaine R. Mardis,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Richard K. Wilson,

    Affiliation: The Genome Institute at Washington University, St. Louis, Missouri, United States of America

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  • Kerstin Howe,

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Paul Flicek,

    Affiliation: The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Tim Hubbard

    Affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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  • Published: July 05, 2011
  • DOI: 10.1371/journal.pbio.1001091

About the Authors

Deanna M. Church, Valerie A. Schneider, Nathan Bouk, Hsiu-Chuan Chen, Richa Agarwala
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America
Tina Graves, Derek Albracht, Milinn Kremitzki, Susan Rock, Holland Kotkiewicz, Colin Kremitzki, Aye Wollam, Lee Trani, Lucinda Fulton, Robert Fulton, George Weinstock, Elaine R. Mardis, Richard K. Wilson
The Genome Institute at Washington University, St. Louis, Missouri, United States of America
Katherine Auger, Lucy Matthews, Siobhan Whitehead, Will Chow, James Torrance, Matthew Dunn, Glenn Harden, Glen Threadgold, Jonathan Wood, Joanna Collins, Paul Heath, Guy Griffiths, Sarah Pelan, Darren Grafham, Kerstin Howe, Tim Hubbard
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
Fiona Cunningham, William M. McLaren, Graham R.S. Ritchie, Paul Flicek
The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
Evan E. Eichler
Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, United States of America
Evan E. Eichler
Howard Hughes Medical Institute, Seattle, Washington, United States of America

Corresponding Author

Email: church@ncbi.nlm.nih.gov

Competing Interests

I have read the journal's policy and have the following conflicts: Paul Flicek is married to the deputy editor of PLoS Medicine, Melissa Norton. Evan Eichler is on the board of Pacific Biosciences.