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Research Article

Premitotic Assembly of Human CENPs -T and -W Switches Centromeric Chromatin to a Mitotic State

  • Lisa Prendergast,

    Affiliation: Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland

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  • Chelly van Vuuren,

    Affiliation: Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland

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  • Agnieszka Kaczmarczyk,

    Affiliation: Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland

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  • Volker Doering,

    Affiliation: Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany

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  • Daniela Hellwig,

    Affiliation: Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany

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  • Nadine Quinn,

    Affiliation: Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland

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  • Christian Hoischen,

    Affiliation: Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany

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  • Stephan Diekmann,

    Affiliation: Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany

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  • Kevin F. Sullivan mail

    kevin.sullivan@nuigalway.ie

    Affiliation: Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland

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  • Published: June 14, 2011
  • DOI: 10.1371/journal.pbio.1001082

About the Authors

Lisa Prendergast, Chelly van Vuuren, Agnieszka Kaczmarczyk, Nadine Quinn, Kevin F. Sullivan
Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland
Volker Doering, Daniela Hellwig, Christian Hoischen, Stephan Diekmann
Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany

Corresponding Author

Email: kevin.sullivan@nuigalway.ie

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: LP CvV SD KFS. Performed the experiments: LP CvV AK NQ VD DH CH KFS. Analyzed the data: LP CvV AK NQ VD DH SD KFS. Contributed reagents/materials/analysis tools: LP CvV AK NQ DH CH KFS. Wrote the paper: LP SD KFS.