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Research Article

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

  • Tobias Steinfeldt,

    Affiliation: Institute for Genetics, University of Cologne, Cologne, Germany

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  • Stephanie Könen-Waisman,

    Affiliation: Institute for Genetics, University of Cologne, Cologne, Germany

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  • Lan Tong,

    Affiliation: Institute for Genetics, University of Cologne, Cologne, Germany

    Current address: Miltenyi Biotec GmbH, Friedrich-Ebert-Strasse 68, 51429 Bergisch Gladbach, Germany.

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  • Nikolaus Pawlowski,

    Affiliation: Institute for Genetics, University of Cologne, Cologne, Germany

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  • Tobias Lamkemeyer,

    Affiliations: Institute for Genetics, University of Cologne, Cologne, Germany, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany

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  • L. David Sibley,

    Affiliation: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Julia P. Hunn,

    Affiliation: Institute for Genetics, University of Cologne, Cologne, Germany

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  • Jonathan C. Howard mail

    j.howard@uni-koeln.de

    Affiliation: Institute for Genetics, University of Cologne, Cologne, Germany

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  • Published: December 21, 2010
  • DOI: 10.1371/journal.pbio.1000576

About the Authors

Tobias Steinfeldt, Stephanie Könen-Waisman, Lan Tong, Nikolaus Pawlowski, Tobias Lamkemeyer, Julia P. Hunn, Jonathan C. Howard
Institute for Genetics, University of Cologne, Cologne, Germany
Tobias Lamkemeyer
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany
L. David Sibley
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Corresponding Author

Email: j.howard@uni-koeln.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: TS LT NP JPH JCH. Performed the experiments: TS SKW LT TL JPH. Analyzed the data: TS SKW LT NP TL JPH JCH. Contributed reagents/materials/analysis tools: TL LDS JCH. Wrote the paper: TS NP TL JPH JCH.