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Research Article

Attenuated T Cell Responses to a High-Potency Ligand In Vivo

  • Emily Corse,

    Affiliation: Department of Immunology, Howard Hughes Medical Institute and Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Rachel A. Gottschalk,

    Affiliations: Department of Immunology, Howard Hughes Medical Institute and Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America

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  • Michelle Krogsgaard,

    Affiliation: Department of Pathology and New York University (NYU) Cancer Institute, NYU School of Medicine, New York, New York, United States of America

    X
  • James P. Allison mail

    allisonj@mskcc.org

    Affiliation: Department of Immunology, Howard Hughes Medical Institute and Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Published: September 14, 2010
  • DOI: 10.1371/journal.pbio.1000481

About the Authors

Emily Corse, Rachel A. Gottschalk, James P. Allison
Department of Immunology, Howard Hughes Medical Institute and Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
Rachel A. Gottschalk
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America
Michelle Krogsgaard
Department of Pathology and New York University (NYU) Cancer Institute, NYU School of Medicine, New York, New York, United States of America

Corresponding Author

Email: allisonj@mskcc.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: EC RAG MK JPA. Performed the experiments: EC RAG MK. Analyzed the data: EC MK. Contributed reagents/materials/analysis tools: MK. Wrote the paper: EC MK JPA.