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Research Article

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

  • Daniel J. Gough,

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia, New York University Langone Medical Center, New York, New York, United States of America

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  • Nicole L. Messina,

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia

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  • Linda Hii,

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia

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  • Jodee A. Gould,

    Affiliation: Centre for Innate Immunity and Infectious Disease, Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia

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  • Kanaga Sabapathy,

    Affiliation: National Cancer Centre, Singapore, Singapore

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  • Ashley P. S. Robertson,

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia

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  • Joseph A. Trapani,

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia

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  • David E. Levy,

    Affiliation: New York University Langone Medical Center, New York, New York, United States of America

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  • Paul J. Hertzog,

    Affiliation: Centre for Innate Immunity and Infectious Disease, Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia

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  • Christopher J. P. Clarke mail,

    chris.clarke@petermac.org (CJPC); ricky.johnstone@petermac.org (RWJ)

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia

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  • Ricky W. Johnstone mail

    chris.clarke@petermac.org (CJPC); ricky.johnstone@petermac.org (RWJ)

    Affiliations: Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, University of Melbourne, Melbourne, Victoria, Australia

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  • Published: April 27, 2010
  • DOI: 10.1371/journal.pbio.1000361

About the Authors

Daniel J. Gough, Nicole L. Messina, Linda Hii, Ashley P. S. Robertson, Joseph A. Trapani, Christopher J. P. Clarke, Ricky W. Johnstone
Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
Daniel J. Gough, Nicole L. Messina, Linda Hii, Ashley P. S. Robertson, Joseph A. Trapani, Christopher J. P. Clarke, Ricky W. Johnstone
University of Melbourne, Melbourne, Victoria, Australia
Daniel J. Gough, David E. Levy
New York University Langone Medical Center, New York, New York, United States of America
Jodee A. Gould, Paul J. Hertzog
Centre for Innate Immunity and Infectious Disease, Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia
Kanaga Sabapathy
National Cancer Centre, Singapore, Singapore

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: JAT DEL PJH CJC RWJ. Performed the experiments: DJG NLM LH JAG APSR CJC. Analyzed the data: DJG NLM LH JAG APSR JAT CJC RWJ. Contributed reagents/materials/analysis tools: KS DEL PJH. Wrote the paper: DJG PJH CJC RWJ.