Advertisement
Research Article

Need-Based Up-Regulation of Protein Levels in Response to Deletion of Their Duplicate Genes

  • Alexander DeLuna equal contributor,

    equal contributor Contributed equally to this work with: Alexander DeLuna, Michael Springer

    Affiliations: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Laboratorio Nacional de Genómica para la Biodiversidad, CINVESTAV, Irapuato, Guanajuato, Mexico

    X
  • Michael Springer equal contributor,

    equal contributor Contributed equally to this work with: Alexander DeLuna, Michael Springer

    Affiliation: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Marc W. Kirschner,

    Affiliation: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Roy Kishony mail

    roy_kishony@hms.harvard.edu

    Affiliations: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America

    X
  • Published: March 30, 2010
  • DOI: 10.1371/journal.pbio.1000347

About the Authors

Alexander DeLuna, Michael Springer, Marc W. Kirschner, Roy Kishony
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
Alexander DeLuna
Laboratorio Nacional de Genómica para la Biodiversidad, CINVESTAV, Irapuato, Guanajuato, Mexico
Roy Kishony
School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: roy_kishony@hms.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: AD MS RK. Performed the experiments: AD MS. Analyzed the data: AD MS RK. Contributed reagents/materials/analysis tools: AD MS MWK RK. Wrote the paper: AD MS MWK RK.