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Research Article

Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD

  • Kihoon Han equal contributor,

    equal contributor Contributed equally to this work with: Kihoon Han, Myoung-Hwan Kim

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Myoung-Hwan Kim equal contributor,

    equal contributor Contributed equally to this work with: Kihoon Han, Myoung-Hwan Kim

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

    X
  • Daniel Seeburg,

    Affiliations: The Picower Institute for Learning and Memory, RIKEN-MIT Neuroscience Research Center, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Jinsoo Seo,

    Affiliation: Department of Physiology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea

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  • Chiara Verpelli,

    Affiliation: CNR Institute of Neuroscience and Department of Neurological Sciences, University of Milan, Milan, Italy

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  • Seungnam Han,

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Hye Sun Chung,

    Affiliation: Department of Anatomy and Division of Brain Korea 21 Biomedical Science, College of Medicine, Korea University, Seoul, Korea

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  • Jaewon Ko,

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Hyun Woo Lee,

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Karam Kim,

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Won Do Heo,

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Tobias Meyer,

    Affiliation: Department of Chemical and Systems Biology, Stanford University, Stanford, California, United States of America

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  • Hyun Kim,

    Affiliation: Department of Anatomy and Division of Brain Korea 21 Biomedical Science, College of Medicine, Korea University, Seoul, Korea

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  • Carlo Sala,

    Affiliation: CNR Institute of Neuroscience and Department of Neurological Sciences, University of Milan, Milan, Italy

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  • Se-Young Choi,

    Affiliation: Department of Physiology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea

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  • Morgan Sheng,

    Affiliations: The Picower Institute for Learning and Memory, RIKEN-MIT Neuroscience Research Center, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Eunjoon Kim mail

    kime@kaist.ac.kr

    Affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea

    Current address: Department of Biological Sciences, Korea Advances Institute of Science and Technology (KAIST), Daejeon, Korea

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  • Published: September 08, 2009
  • DOI: 10.1371/journal.pbio.1000187

About the Authors

Kihoon Han, Myoung-Hwan Kim, Seungnam Han, Jaewon Ko, Hyun Woo Lee, Karam Kim, Won Do Heo, Eunjoon Kim
National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea
Daniel Seeburg, Morgan Sheng
The Picower Institute for Learning and Memory, RIKEN-MIT Neuroscience Research Center
Daniel Seeburg, Morgan Sheng
Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Jinsoo Seo, Se-Young Choi
Department of Physiology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea
Chiara Verpelli, Carlo Sala
CNR Institute of Neuroscience and Department of Neurological Sciences, University of Milan, Milan, Italy
Hye Sun Chung, Hyun Kim
Department of Anatomy and Division of Brain Korea 21 Biomedical Science, College of Medicine, Korea University, Seoul, Korea
Tobias Meyer
Department of Chemical and Systems Biology, Stanford University, Stanford, California, United States of America

Corresponding Author

Email: kime@kaist.ac.kr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: KH MHK. Performed the experiments: KH MHK DS JS CV SH HSC JK HWL KK HK. Analyzed the data: KH MHK DS JS CS SYC MS. Contributed reagents/materials/analysis tools: WDH TM. Wrote the paper: EK.