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Research Article

Glia and Muscle Sculpt Neuromuscular Arbors by Engulfing Destabilized Synaptic Boutons and Shed Presynaptic Debris

  • Yuly Fuentes-Medel,

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Mary A. Logan,

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • James Ashley,

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Bulent Ataman,

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Vivian Budnik mail,

    vivian.budnik@umassmed.edu (VB); marc.freeman@umassmed.edu (MRF)

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Marc R. Freeman mail

    vivian.budnik@umassmed.edu (VB); marc.freeman@umassmed.edu (MRF)

    Affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Published: August 25, 2009
  • DOI: 10.1371/journal.pbio.1000184

About the Authors

Yuly Fuentes-Medel, Mary A. Logan, James Ashley, Bulent Ataman, Vivian Budnik, Marc R. Freeman
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: YFM MAL JA VB MRF. Performed the experiments: YFM MAL JA BA. Analyzed the data: YFM MAL JA VB MRF. Contributed reagents/materials/analysis tools: YFM MAL JA BA VB MRF. Wrote the paper: YFM MAL JA VB MRF.