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Research Article

Specificity and Plasticity of Thalamocortical Connections in Sema6A Mutant Mice

  • Graham E Little equal contributor,

    equal contributor Contributed equally to this work with: Graham E Little, Guillermina López-Bendito

    Affiliation: Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland

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  • Guillermina López-Bendito equal contributor mail,

    equal contributor Contributed equally to this work with: Graham E Little, Guillermina López-Bendito

    To whom correspondence should be addressed. E-mail: g.lbendito@umh.es (GL-B); zoltan.molnar@dpag.ox.ac.uk (ZM); Kevin.Mitchell@tcd.ie (KJM)

    Affiliations: Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom, Instituto de Neurociencias de Alicante, CSIC & Universidad Miguel Hernández, San't Joan d'Alacant, Spain

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  • Annette E Rünker,

    Affiliation: Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland

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  • Noelia García,

    Affiliation: Instituto de Neurociencias de Alicante, CSIC & Universidad Miguel Hernández, San't Joan d'Alacant, Spain

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  • Maria C Piñon,

    Affiliation: Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Alain Chédotal,

    Affiliations: INSERM, UMR S968, Institut de la Vision, Department of Development, Paris, France, UPMC Univ Paris 06, UMR S968, Institut de la Vision, Paris, France

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  • Zoltán Molnár mail,

    To whom correspondence should be addressed. E-mail: g.lbendito@umh.es (GL-B); zoltan.molnar@dpag.ox.ac.uk (ZM); Kevin.Mitchell@tcd.ie (KJM)

    Affiliation: Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Kevin J Mitchell mail

    To whom correspondence should be addressed. E-mail: g.lbendito@umh.es (GL-B); zoltan.molnar@dpag.ox.ac.uk (ZM); Kevin.Mitchell@tcd.ie (KJM)

    Affiliation: Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland

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  • Published: April 28, 2009
  • DOI: 10.1371/journal.pbio.1000098

About the Authors

Graham E Little, Annette E Rünker, Kevin J Mitchell
Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland
Guillermina López-Bendito, Maria C Piñon, Zoltán Molnár
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom
Guillermina López-Bendito, Noelia García
Instituto de Neurociencias de Alicante, CSIC & Universidad Miguel Hernández, San't Joan d'Alacant, Spain
Alain Chédotal
INSERM, UMR S968, Institut de la Vision, Department of Development, Paris, France
Alain Chédotal
UPMC Univ Paris 06, UMR S968, Institut de la Vision, Paris, France

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

GEL, GL-B, AER, ZM, and KJM conceived and designed the experiments. GEL, GL-B, AER, NG, MCP, AC, and ZM performed the experiments. GEL, GL-B, AER, NG, MCP, ZM, and KJM analyzed the data. AC contributed reagents/materials/analysis tools. GEL, GL-B, ZM, and KJM wrote the paper.