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Research Article

Structural Studies of the Giant Mimivirus

  • Chuan Xiao,

    Affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

    ¤ Current address: Department of Chemistry, University of Texas, El Paso, Texas, United States of America

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  • Yurii G Kuznetsov,

    Affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, California, United States of America

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  • Siyang Sun,

    Affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

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  • Susan L Hafenstein,

    Affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

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  • Victor A Kostyuchenko,

    Affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

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  • Paul R Chipman,

    Affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

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  • Marie Suzan-Monti,

    Affiliation: Unité des Rickettsies, Faculté de Médecine (CNRS) UMR 6020, IFR 48, Marseille, France

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  • Didier Raoult,

    Affiliation: Unité des Rickettsies, Faculté de Médecine (CNRS) UMR 6020, IFR 48, Marseille, France

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  • Alexander McPherson,

    Affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, California, United States of America

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  • Michael G Rossmann mail

    To whom correspondence should be addressed. E-mail: mr@purdue.edu

    Affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

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  • Published: April 28, 2009
  • DOI: 10.1371/journal.pbio.1000092

About the Authors

Chuan Xiao, Siyang Sun, Susan L Hafenstein, Victor A Kostyuchenko, Paul R Chipman, Michael G Rossmann
Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America
Yurii G Kuznetsov, Alexander McPherson
Department of Molecular Biology and Biochemistry, University of California, Irvine, California, United States of America
Marie Suzan-Monti, Didier Raoult
Unité des Rickettsies, Faculté de Médecine (CNRS) UMR 6020, IFR 48, Marseille, France

Corresponding Author

Email: mr@purdue.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MGR conceived and designed the experiments. CX, YGK, SS, PRC, MSM, DR, AMcP, and MGR performed the experiments. PRC performed EM data collection. DR performed Mimivirus studies in Marseilles. AmcP perofmed AFM investigations on the virus. CX, SS, VAK analyzed the data. SS, SLH, and MSM contributed reagents/materials/analysis tools. MSM performed virus propagation. CX and MGR wrote the paper.