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Research Article

BEAF Regulates Cell-Cycle Genes through the Controlled Deposition of H3K9 Methylation Marks into Its Conserved Dual-Core Binding Sites

  • Eldon Emberly equal contributor mail,

    equal contributor Contributed equally to this work with: Eldon Emberly, Olivier Cuvier

    To whom correspondence should be addressed. E-mail: eemberly@sfu.ca (EE); cuvier@igh.cnrs.fr (OC)

    Affiliation: Physics Department, Simon Fraser University, Burnaby, British Columbia, Canada

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  • Roxane Blattes,

    Affiliation: CNRS, Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse, UPS, France

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  • Bernd Schuettengruber,

    Affiliation: Department of Biological Sciences, Louisiana State University, Baton Rouge, Lousiana, United States of America

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  • Magali Hennion,

    Affiliations: CNRS, Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse, UPS, France, Institut de Genetique Humaine, Department of Genome Dynamics, CNRS, Montpelier, France

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  • Nan Jiang,

    Affiliation: Department of Biological Sciences, Louisiana State University, Baton Rouge, Lousiana, United States of America

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  • Craig M Hart,

    Affiliation: Department of Biological Sciences, Louisiana State University, Baton Rouge, Lousiana, United States of America

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  • Emmanuel Käs,

    Affiliation: CNRS, Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse, UPS, France

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  • Olivier Cuvier equal contributor mail

    equal contributor Contributed equally to this work with: Eldon Emberly, Olivier Cuvier

    To whom correspondence should be addressed. E-mail: eemberly@sfu.ca (EE); cuvier@igh.cnrs.fr (OC)

    Affiliation: Institut de Genetique Humaine, Department of Genome Dynamics, CNRS, Montpelier, France

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  • Published: December 23, 2008
  • DOI: 10.1371/journal.pbio.0060327

About the Authors

Eldon Emberly
Physics Department, Simon Fraser University, Burnaby, British Columbia, Canada
Roxane Blattes, Magali Hennion, Emmanuel Käs
CNRS, Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse, UPS, France
Bernd Schuettengruber, Nan Jiang, Craig M Hart
Department of Biological Sciences, Louisiana State University, Baton Rouge, Lousiana, United States of America
Magali Hennion, Olivier Cuvier
Institut de Genetique Humaine, Department of Genome Dynamics, CNRS, Montpelier, France

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

OC conceived and designed the experiments. EE, RB, BS, MH, NJ, and OC performed the experiments. EE, RB, BS, MH, NJ, CMH, EK, and OC analyzed the data. EE, BS, MH, NJ, CMH, EK, and OC contributed reagents/materials/analysis tools. OC wrote the paper.