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Research Article

Drosophila Neurotrophins Reveal a Common Mechanism for Nervous System Formation

  • Bangfu Zhu equal contributor,

    equal contributor Contributed equally to this work with: Bangfu Zhu, Jenny A Pennack

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Jenny A Pennack equal contributor,

    equal contributor Contributed equally to this work with: Bangfu Zhu, Jenny A Pennack

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Peter McQuilton,

    Affiliations: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom, Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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  • Manuel G Forero,

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Kenji Mizuguchi,

    Affiliations: Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom, Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, United Kingdom, National Institute of Biomedical Innovation, Osaka, Japan

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  • Ben Sutcliffe,

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Chun-Jing Gu,

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Janine C Fenton,

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Alicia Hidalgo mail

    To whom correspondence should be addressed. E-mail: a.hidalgo@bham.ac.uk

    Affiliation: Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

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  • Published: November 18, 2008
  • DOI: 10.1371/journal.pbio.0060284

About the Authors

Bangfu Zhu, Jenny A Pennack, Peter McQuilton, Manuel G Forero, Ben Sutcliffe, Chun-Jing Gu, Janine C Fenton, Alicia Hidalgo
Neurodevelopment Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom
Peter McQuilton
Department of Genetics, University of Cambridge, Cambridge, United Kingdom
Kenji Mizuguchi
Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
Kenji Mizuguchi
Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, United Kingdom
Kenji Mizuguchi
National Institute of Biomedical Innovation, Osaka, Japan

Corresponding Author

Email: a.hidalgo@bham.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

BZ, PM, KM, and AH conceived and designed the experiments. BZ, JAP, PM, BS, C-JG, JCF, and AH performed the experiments. BZ, JAP, PM, MGF, KM, BS, and AH analyzed the data. MGF contributed reagents/materials/analysis tools. AH wrote the paper.