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Research Article

Immunoglobulin Heavy Chain Exclusion in the Shark

  • Karolina Malecek,

    Affiliation: Department of Physiology and Pharmacology, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States of America

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  • Victor Lee,

    Affiliation: Department of Physiology and Pharmacology, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States of America

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  • Wendy Feng,

    Affiliation: Department of Physiology and Pharmacology, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States of America

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  • Jing Li Huang,

    Affiliation: Department of Physiology and Pharmacology, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States of America

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  • Martin F Flajnik,

    Affiliation: Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland, United States of America

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  • Yuko Ohta,

    Affiliation: Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland, United States of America

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  • Ellen Hsu mail

    To whom correspondence should be addressed. E-mail: hsue@hscbklyn.edu

    Affiliation: Department of Physiology and Pharmacology, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States of America

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  • Published: June 24, 2008
  • DOI: 10.1371/journal.pbio.0060157

About the Authors

Karolina Malecek, Victor Lee, Wendy Feng, Jing Li Huang, Ellen Hsu
Department of Physiology and Pharmacology, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, United States of America
Martin F Flajnik, Yuko Ohta
Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland, United States of America

Corresponding Author

Email: hsue@hscbklyn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KM and EH conceived and designed the experiments. KM, VL, WF, and YO performed the experiments. KM and EH analyzed the data. KM, VL, JLH, MFF, and YO contributed reagents/materials/analysis tools. EH wrote the paper.