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Research Article

Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation

  • Sushma Shivaswamy equal contributor,

    equal contributor Contributed equally to this work with: Sushma Shivaswamy, Akshay Bhinge

    Affiliation: Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, and Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas, United States of America

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  • Akshay Bhinge equal contributor,

    equal contributor Contributed equally to this work with: Sushma Shivaswamy, Akshay Bhinge

    Affiliation: Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, and Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas, United States of America

    X
  • Yongjun Zhao,

    Affiliation: Michael Smith Genome Sciences Center, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

    X
  • Steven Jones,

    Affiliation: Michael Smith Genome Sciences Center, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

    X
  • Martin Hirst,

    Affiliation: Michael Smith Genome Sciences Center, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

    X
  • Vishwanath R Iyer mail

    To whom correspondence should be addressed. E-mail: vishy@mail.utexas.edu

    Affiliation: Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, and Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas, United States of America

    X
  • Published: March 18, 2008
  • DOI: 10.1371/journal.pbio.0060065

About the Authors

Sushma Shivaswamy, Akshay Bhinge, Vishwanath R Iyer
Institute for Cellular and Molecular Biology, Center for Systems and Synthetic Biology, and Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas, United States of America
Yongjun Zhao, Steven Jones, Martin Hirst
Michael Smith Genome Sciences Center, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

Corresponding Author

Email: vishy@mail.utexas.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SS performed the experiments and wrote the paper. AB analyzed the data and contributed reagents/materials/analysis tools. YZ, SJ, and MH contributed reagents/materials/analysis tools. VRI conceived and designed the experiments and wrote the paper.