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Research Article

Amyloid as a Depot for the Formulation of Long-Acting Drugs

  • Samir K Maji,

    Affiliation: Structural Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • David Schubert,

    Affiliation: Cellular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • Catherine Rivier,

    Affiliation: The Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • Soon Lee,

    Affiliation: The Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • Jean E Rivier,

    Affiliation: The Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • Roland Riek mail

    To whom correspondence should be addressed. E-mail: riek@salk.edu

    Affiliations: Structural Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America, Laboratory for Physical Chemistry, Zurich, Switzerland

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  • Published: February 05, 2008
  • DOI: 10.1371/journal.pbio.0060017

About the Authors

Samir K Maji, Roland Riek
Structural Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America
David Schubert
Cellular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America
Catherine Rivier, Soon Lee, Jean E Rivier
The Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America
Roland Riek
Laboratory for Physical Chemistry, Zurich, Switzerland

Corresponding Author

Email: riek@salk.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SKM, DS, CR, and RR conceived and designed the experiments. SKM, CR, and SL performed the experiments. SKM and RR analyzed the data. JER contributed reagents/materials/analysis tools. SKM, DS, CR, JER, and RR wrote the paper.