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Research Article

The Signal Sequence Coding Region Promotes Nuclear Export of mRNA

  • Alexander F Palazzo,

    Affiliation: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Michael Springer,

    Affiliation: Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Yoko Shibata,

    Affiliation: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Chung-Sheng Lee,

    Affiliation: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Anusha P Dias,

    Affiliation: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Tom A Rapoport mail

    To whom correspondence should be addressed. E-mail: tom_rapoport@hms.harvard.edu

    Affiliation: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: December 04, 2007
  • DOI: 10.1371/journal.pbio.0050322

About the Authors

Alexander F Palazzo, Yoko Shibata, Chung-Sheng Lee, Anusha P Dias, Tom A Rapoport
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
Michael Springer
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

Email: tom_rapoport@hms.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AFP and TAR conceived and designed the experiments. AFP, YS, CSL, and APD performed the experiments. AFP and MS analyzed the data. AFP, MS and TAR contributed reagents/materials/analysis tools. AFP, MS, and TAR wrote the paper. MS designed algorithms used for genome-wide analysis, and conceived and designed the bioinformatic analysis.