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Research Article

Incomplete and Inaccurate Vocal Imitation after Knockdown of FoxP2 in Songbird Basal Ganglia Nucleus Area X

  • Sebastian Haesler,

    Affiliations: Max-Planck-Institute for Molecular Genetics, Berlin, Germany, Institut für Verhaltensbiologie, Freie Universität Berlin, Berlin, Germany

    ¤ Current address: Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Christelle Rochefort,

    Affiliations: Max-Planck-Institute for Molecular Genetics, Berlin, Germany, Institut für Verhaltensbiologie, Freie Universität Berlin, Berlin, Germany

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  • Benjamin Georgi,

    Affiliation: Max-Planck-Institute for Molecular Genetics, Berlin, Germany

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  • Pawel Licznerski,

    Affiliation: Max-Planck-Institute for Medical Research, Heidelberg, Germany

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  • Pavel Osten,

    Affiliation: Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Constance Scharff mail

    To whom correspondence should be addressed. E-mail: scharff@zedat.fu-berlin.de

    Affiliations: Max-Planck-Institute for Molecular Genetics, Berlin, Germany, Institut für Verhaltensbiologie, Freie Universität Berlin, Berlin, Germany

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  • Published: December 04, 2007
  • DOI: 10.1371/journal.pbio.0050321

About the Authors

Sebastian Haesler, Christelle Rochefort, Benjamin Georgi, Constance Scharff
Max-Planck-Institute for Molecular Genetics, Berlin, Germany
Sebastian Haesler, Christelle Rochefort, Constance Scharff
Institut für Verhaltensbiologie, Freie Universität Berlin, Berlin, Germany
Pawel Licznerski
Max-Planck-Institute for Medical Research, Heidelberg, Germany
Pavel Osten
Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

Corresponding Author

Email: scharff@zedat.fu-berlin.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SH and CS conceived and designed the experiments. SH and CR performed the experiments. SH analyzed the data. CR performed analysis of long-term changes in neuronal viability after knockdown. BG performed song sequence analysis. BG, PL, PO, and CS contributed reagents/materials and analysis tools. SH and CS wrote the paper.