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Research Article

Bioassay-Guided Evolution of Glycosylated Macrolide Antibiotics in Escherichia coli

  • Ho Young Lee,

    Affiliation: Department of Chemistry, Stanford University, Stanford, California, United States of America

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  • Chaitan Khosla mail

    To whom correspondence should be addressed. E-mail: khosla@stanford.edu

    Affiliations: Department of Chemistry, Stanford University, Stanford, California, United States of America, Department of Chemical Engineering, Stanford University, Stanford, California, United States of America

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  • Published: February 06, 2007
  • DOI: 10.1371/journal.pbio.0050045

About the Authors

Ho Young Lee, Chaitan Khosla
Department of Chemistry, Stanford University, Stanford, California, United States of America
Chaitan Khosla
Department of Chemical Engineering, Stanford University, Stanford, California, United States of America

Corresponding Author

Email: khosla@stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

HYL and CK conceived and designed the experiments. HYL performed the experiments and analyzed the data. HYL and CK wrote the paper.