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Research Article

Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes

  • Michal Sharon,

    Affiliation: Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

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  • Thomas Taverner,

    Affiliation: Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Xavier I Ambroggio,

    Affiliation: Division of Biology, California Institute of Technology, Pasadena, California, United States of America

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  • Raymond J Deshaies,

    Affiliation: Division of Biology, California Institute of Technology, Pasadena, California, United States of America

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  • Carol V Robinson mail

    To whom correspondence should be addressed. E-mail: cvr24@cam.ac.uk

    Affiliation: Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Published: August 01, 2006
  • DOI: 10.1371/journal.pbio.0040267

About the Authors

Michal Sharon, Thomas Taverner, Carol V Robinson
Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
Xavier I Ambroggio, Raymond J Deshaies
Division of Biology, California Institute of Technology, Pasadena, California, United States of America

Corresponding Author

Email: cvr24@cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MS, RJD, and CVR conceived and designed the experiments. MS and TT performed the experiments. MS and TT analyzed the data. XIA and RJD contributed reagents/materials/analysis tools. MS, RJD, and CVR wrote the paper.