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Research Article

Dynamic Interaction of TTDA with TFIIH Is Stabilized by Nucleotide Excision Repair in Living Cells

  • Giuseppina Giglia-Mari equal contributor,

    equal contributor Contributed equally to this work with: Giuseppina Giglia-Mari, Catherine Miquel

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Catherine Miquel equal contributor,

    equal contributor Contributed equally to this work with: Giuseppina Giglia-Mari, Catherine Miquel

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Arjan F Theil,

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Pierre-Olivier Mari,

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Deborah Hoogstraten,

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Jessica M. Y Ng,

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Christoffel Dinant,

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Jan H. J Hoeijmakers,

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Wim Vermeulen mail

    To whom correspondence should be addressed. E-mail: w.vermeulen@erasmusmc.nl

    Affiliation: Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

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  • Published: May 09, 2006
  • DOI: 10.1371/journal.pbio.0040156

About the Authors

Giuseppina Giglia-Mari, Catherine Miquel, Arjan F Theil, Pierre-Olivier Mari, Deborah Hoogstraten, Jessica M. Y Ng, Christoffel Dinant, Jan H. J Hoeijmakers, Wim Vermeulen
Department of Cell Biology and Genetics, Medical Genetics Center, Erasmus Medical Center, Rotterdam, Netherlands

Corresponding Author

Email: w.vermeulen@erasmusmc.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

GGM and WV conceived and designed the experiments. GGM, CM, and AFT performed the experiments. GGM, CM, and POM analyzed the data. DH, JMYN, and CD contributed reagents/materials/analysis tools. GGM, JHJH, and WV wrote the paper.