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Research Article

Determination of Stromal Signatures in Breast Carcinoma

  • Robert B West,

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

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  • Dimitry S. A Nuyten,

    Affiliation: Division of Diagnostic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands

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  • Subbaya Subramanian,

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

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  • Torsten O Nielsen,

    Affiliation: Department of Pathology and Genetic Pathology Evaluation Centre, Vancouver General Hospital, Vancouver BC, United States of America

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  • Christopher L Corless,

    Affiliation: Department of Pathology and OHSU Cancer Institute, Oregon Health and Science University, Portland, Oregon, United States of America

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  • Brian P Rubin,

    Affiliation: Department of Anatomic Pathology, University of Washington Medical Center, Seattle, Washington, United States of America

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  • Kelli Montgomery,

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

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  • Shirley Zhu,

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

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  • Rajiv Patel,

    Affiliation: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Tina Hernandez-Boussard,

    Affiliation: Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America

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  • John R Goldblum,

    Affiliation: Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America

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  • Patrick O Brown,

    Affiliation: Deparment of Biochemistry and Howard Hughes Medical Institute, Stanford University Medical Center, Stanford, California, United States of America

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  • Marc van de Vijver,

    Affiliation: Division of Diagnostic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands

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  • Matt van de Rijn mail

    To whom correspondence should be addressed. E-mail: mrijn@stanford.edu

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

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  • Published: May 10, 2005
  • DOI: 10.1371/journal.pbio.0030187

About the Authors

Robert B West, Subbaya Subramanian, Kelli Montgomery, Shirley Zhu, Matt van de Rijn
Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America
Dimitry S. A Nuyten, Marc van de Vijver
Division of Diagnostic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands
Torsten O Nielsen
Department of Pathology and Genetic Pathology Evaluation Centre, Vancouver General Hospital, Vancouver BC, United States of America
Christopher L Corless
Department of Pathology and OHSU Cancer Institute, Oregon Health and Science University, Portland, Oregon, United States of America
Brian P Rubin
Department of Anatomic Pathology, University of Washington Medical Center, Seattle, Washington, United States of America
Rajiv Patel
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America
Tina Hernandez-Boussard
Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America
John R Goldblum
Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America
Patrick O Brown
Deparment of Biochemistry and Howard Hughes Medical Institute, Stanford University Medical Center, Stanford, California, United States of America

Corresponding Author

Email: mrijn@stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RBW, DSAN, POB, MvdV, and MvdR conceived and designed the experiments. RBW, DSAN, POB, MvdV, and MvdR analyzed the data. RBW, DSAN, SS, KM, and SZ performed the experiments. RBW, DSAN, SS, TON, CLC, BPR, RP, TH-B, JRG, POB, MvdV, and MvdR contributed reagents/materials/analysis tools. RBW, DSAN, SS, TON, CLC, BPR, POB, MvdV, and MvdR wrote the paper.