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Research Article

Regulatory Variation at Glypican-3 Underlies a Major Growth QTL in Mice

  • Fiona Oliver equal contributor,

    equal contributor Contributed equally to this work with: Fiona Oliver, Julian K Christians

    Affiliation: University of Edinburgh, Institute of Evolutionary Biology, School of Biological Sciences, Edinburgh, United Kingdom

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  • Julian K Christians equal contributor mail,

    equal contributor Contributed equally to this work with: Fiona Oliver, Julian K Christians

    To whom correspondence should be addressed. E-mail: julian.christians@ed.ac.uk

    Affiliation: University of Edinburgh, Institute of Evolutionary Biology, School of Biological Sciences, Edinburgh, United Kingdom

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  • Xiaojun Liu,

    Affiliation: University of Edinburgh, Institute of Evolutionary Biology, School of Biological Sciences, Edinburgh, United Kingdom

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  • Susan Rhind,

    Affiliation: Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom

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  • Vinesh Verma,

    Affiliation: University of Edinburgh, Institute of Evolutionary Biology, School of Biological Sciences, Edinburgh, United Kingdom

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  • Claire Davison,

    Affiliation: Medical Research Council Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom

    X
  • Steve D. M Brown,

    Affiliation: Medical Research Council Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom

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  • Paul Denny,

    Affiliation: Medical Research Council Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom

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  • Peter D Keightley

    Affiliation: University of Edinburgh, Institute of Evolutionary Biology, School of Biological Sciences, Edinburgh, United Kingdom

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  • Published: April 05, 2005
  • DOI: 10.1371/journal.pbio.0030135

About the Authors

Fiona Oliver, Julian K Christians, Xiaojun Liu, Vinesh Verma, Peter D Keightley
University of Edinburgh, Institute of Evolutionary Biology, School of Biological Sciences, Edinburgh, United Kingdom
Susan Rhind
Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom
Claire Davison, Steve D. M Brown, Paul Denny
Medical Research Council Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom

Corresponding Author

Email: julian.christians@ed.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

FO, JKC, SDMB, PD, and PDK conceived and designed the experiments. FO, JKC, XL, SR, VV, and CD performed the experiments. FO, JKC, and PDK analyzed the data. FO, JKC, and PDK wrote the paper.