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Research Article

Functional Evolution of a cis-Regulatory Module

  • Michael Z Ludwig mail,

    To whom correspondence should be addressed. E-mail: mludwig@midway.uchicago.edu

    Affiliation: Department of Ecology and Evolution, University of Chicago, Illinois, United States of America

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  • Arnar Palsson,

    Affiliation: Department of Ecology and Evolution, University of Chicago, Illinois, United States of America

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  • Elena Alekseeva,

    Affiliation: Department of Ecology and Evolution, University of Chicago, Illinois, United States of America

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  • Casey M Bergman,

    Affiliation: Department of Genetics, University of Cambridge, United Kingdom

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  • Janaki Nathan,

    Affiliation: Department of Ecology and Evolution, University of Chicago, Illinois, United States of America

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  • Martin Kreitman

    Affiliation: Department of Ecology and Evolution, University of Chicago, Illinois, United States of America

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  • Published: March 15, 2005
  • DOI: 10.1371/journal.pbio.0030093

About the Authors

Michael Z Ludwig, Arnar Palsson, Elena Alekseeva, Janaki Nathan, Martin Kreitman
Department of Ecology and Evolution, University of Chicago, Illinois, United States of America
Casey M Bergman
Department of Genetics, University of Cambridge, United Kingdom

Corresponding Author

Email: mludwig@midway.uchicago.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MZL and MK conceived and designed the experiments. MZL performed the experiments with EA and JN helping with embryo staining and genotyping. CMB conducted genomic sequence analysis. AP analyzed images. MZL, AP, and MK analyzed the data. MZL and EA contributed reagents/materials/analysis tools. MZL, AP, and MK wrote the paper.