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Research Article

Secreted Bacterial Effectors and Host-Produced Eiger/TNF Drive Death in a Salmonella-Infected Fruit Fly

  • Stephanie M Brandt,

    Affiliation: Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

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  • Marc S Dionne,

    Affiliation: Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

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  • Ranjiv S Khush,

    Affiliation: Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

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  • Linh N Pham,

    Affiliation: Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

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  • Thomas J Vigdal,

    Affiliation: Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

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  • David S Schneider mail

    To whom correspondence should be addressed. E-mail: dschneider@stanford.edu

    Affiliation: Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

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  • Published: November 30, 2004
  • DOI: 10.1371/journal.pbio.0020418

About the Authors

Stephanie M Brandt, Marc S Dionne, Ranjiv S Khush, Linh N Pham, Thomas J Vigdal, David S Schneider
Department of Microbiology and Immunology, Stanford University, Stanford, California, United States of America

Corresponding Author

Email: dschneider@stanford.edu

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

SMB, MSD, RSK, LNP, TJV, and DSS conceived and designed the experiments. SMB, MSD, RSK, LNP, TJV, and DSS performed the experiments. SMB, MSD, RSK, LNP, TJV, and DSS analyzed the data. SMB, MSD, RSK, LNP, and DSS contributed reagents/materials/analysis tools. SMB and DSS wrote the paper.