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Research Article

Convergent Evolution of Chromosomal Sex-Determining Regions in the Animal and Fungal Kingdoms

  • James A Fraser,

    Affiliations: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Stephanie Diezmann,

    Affiliations: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Institute for Genomics Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Ryan L Subaran,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Andria Allen,

    Affiliations: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Institute for Genomics Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Klaus B Lengeler,

    Affiliations: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina, United States of America

    ¤Current address: Institut für Mikrobiologie, Heinrich-Heine-Universität, Düsseldorf, Germany

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  • Fred S Dietrich,

    Affiliations: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Institute for Genomics Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Joseph Heitman mail

    To whom correspondence should be addressed. E-mail: heitm001@duke.edu

    Affiliations: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Published: November 09, 2004
  • DOI: 10.1371/journal.pbio.0020384

About the Authors

James A Fraser, Stephanie Diezmann, Ryan L Subaran, Andria Allen, Klaus B Lengeler, Fred S Dietrich, Joseph Heitman
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
James A Fraser, Klaus B Lengeler, Joseph Heitman
Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina, United States of America
Stephanie Diezmann, Andria Allen, Fred S Dietrich
Duke Institute for Genomics Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America
Joseph Heitman
Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
Joseph Heitman
Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America

Corresponding Author

Email: heitm001@duke.edu

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

JAF and JH conceived and designed the experiments. JAF, RLS, AA, and KL performed the experiments. JAF, SD, FSD, and JH analyzed the data. JAF and FSD contributed reagents/materials/analysis tools. JAF and JH wrote the paper.