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Research Article

Functional Bias and Spatial Organization of Genes in Mutational Hot and Cold Regions in the Human Genome

  • Jeffrey H Chuang,

    Affiliation: Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

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  • Hao Li mail

    To whom correspondence should be addressed. E-mail: haoli@genome.ucsf.edu

    Affiliation: Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

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  • Published: February 17, 2004
  • DOI: 10.1371/journal.pbio.0020029

About the Authors

Jeffrey H Chuang, Hao Li
Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

Corresponding Author

Email: haoli@genome.ucsf.edu

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

JC and HL conceived and designed the experiments. JC performed the experiments. JC and HL analyzed the data. JC contributed reagents/materials/analysis tools. JC wrote the paper.