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Research Article

Transcriptome Analysis of Mouse Stem Cells and Early Embryos

  • Alexei A Sharov,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Yulan Piao,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Ryo Matoba,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Dawood B Dudekula,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Yong Qian,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Vincent VanBuren,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Geppino Falco,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Patrick R Martin,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Carole A Stagg,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Uwem C Bassey,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Yuxia Wang,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Mark G Carter,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Toshio Hamatani,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Kazuhiro Aiba,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Hidenori Akutsu,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Lioudmila Sharova,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Tetsuya S Tanaka,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Wendy L Kimber,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Toshiyuki Yoshikawa,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Saied A Jaradat,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Serafino Pantano,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Ramaiah Nagaraja,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Kenneth R Boheler,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Dennis Taub,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Richard J Hodes,

    Affiliations: National Institute on Aging, Baltimore, Maryland, United States of America, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Dan L Longo,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • David Schlessinger,

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Jonathan Keller,

    Affiliation: Basic Research Program, SAIC–Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

    X
  • Emily Klotz,

    Affiliation: National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Garnett Kelsoe,

    Affiliation: Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Akihiro Umezawa,

    Affiliation: National Research Institute for Child Health and Development, Tokyo, Japan

    X
  • Angelo L Vescovi,

    Affiliation: Institute for Stem Cell Research, Ospedale San Raffaele, Milan, Italy

    X
  • Janet Rossant,

    Affiliation: Mount Sinai Hospital, Toronto, Ontario, Canada

    X
  • Tilo Kunath,

    Affiliation: Mount Sinai Hospital, Toronto, Ontario, Canada

    X
  • Brigid L. M Hogan,

    Affiliation: Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Anna Curci,

    Affiliation: Institute of Genetics and Biophysics, Consiglio Nazionale delle Ricerche, Naples, Italy

    X
  • Michele D'Urso,

    Affiliation: Institute of Genetics and Biophysics, Consiglio Nazionale delle Ricerche, Naples, Italy

    X
  • Janet Kelso,

    Affiliation: South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa

    X
  • Winston Hide,

    Affiliation: South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa

    X
  • Minoru S. H Ko mail

    To whom correspondence should be addressed. E-mail: KoM@grc.nia.nih.gov

    Affiliation: National Institute on Aging, Baltimore, Maryland, United States of America

    X
  • Published: December 22, 2003
  • DOI: 10.1371/journal.pbio.0000074

About the Authors

Alexei A Sharov, Yulan Piao, Ryo Matoba, Dawood B Dudekula, Yong Qian, Vincent VanBuren, Geppino Falco, Patrick R Martin, Carole A Stagg, Uwem C Bassey, Yuxia Wang, Mark G Carter, Toshio Hamatani, Kazuhiro Aiba, Hidenori Akutsu, Lioudmila Sharova, Tetsuya S Tanaka, Wendy L Kimber, Toshiyuki Yoshikawa, Saied A Jaradat, Serafino Pantano, Ramaiah Nagaraja, Kenneth R Boheler, Dennis Taub, Richard J Hodes, Dan L Longo, David Schlessinger, Minoru S. H Ko
National Institute on Aging, Baltimore, Maryland, United States of America
Richard J Hodes, Emily Klotz
National Cancer Institute, Bethesda, Maryland, United States of America
Jonathan Keller
Basic Research Program, SAIC–Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
Garnett Kelsoe, Brigid L. M Hogan
Duke University Medical Center, Durham, North Carolina, United States of America
Akihiro Umezawa
National Research Institute for Child Health and Development, Tokyo, Japan
Angelo L Vescovi
Institute for Stem Cell Research, Ospedale San Raffaele, Milan, Italy
Janet Rossant, Tilo Kunath
Mount Sinai Hospital, Toronto, Ontario, Canada
Anna Curci, Michele D'Urso
Institute of Genetics and Biophysics, Consiglio Nazionale delle Ricerche, Naples, Italy
Janet Kelso, Winston Hide
South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa

Corresponding Author

Email: KoM@grc.nia.nih.gov

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

MSHK conceived and designed the experiments. YP, RM, GF, PRM, CAS, UCB, YW, MGC, TH, KA, HA, LS, TST, WLK, TY, SAJ, SP, and MSHK performed the experiments. AAS, YP, RM, DBD, YQ, VV, GF, J. Kelso, WH, and MSHK analyzed the data. RN, KRB, DDT, RJH, DLL, DS, J. Keller, EK, GHK, AU, AV, JR, TK, BLMH, AC, MD, J. Kelso, and WH contributed reagents/materials/analysis tools. AAS, YP, RM, VV, GF, and MSHK wrote the paper.