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Research Article

Radial Glial Neural Progenitors Regulate Nascent Brain Vascular Network Stabilization Via Inhibition of Wnt Signaling

  • Shang Ma,

    Affiliations: Departments of Neuroscience and Neurology, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Graduate Program in Cellular and Molecular Biology, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Hyo Jun Kwon,

    Affiliations: Departments of Neuroscience and Neurology, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Neuroscience Training Program, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Heidi Johng,

    Affiliation: Departments of Neuroscience and Neurology, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Keling Zang,

    Affiliation: Department of Physiology, University of California–San Francisco, San Francisco, California, United States of America

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  • Zhen Huang mail

    z.huang@neurology.wisc.edu

    Affiliation: Departments of Neuroscience and Neurology, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Published: January 22, 2013
  • DOI: 10.1371/journal.pbio.1001469

Reader Comments (1)

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Research subject and how it is adressed

Posted by jedsrose on 24 Jan 2013 at 22:15 GMT

This is a very interesting article. In this case, the kind of subject of research (brain development) the use of regulatory signals that depends upon changes in gene expression are perfectly adequate. However, it is important to keep in mind that those fast regulatory mechanisms (that by being fast cannot depend upon changes in gene expression) are also playing its role.

No competing interests declared.