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Research Article

Innate-Like Control of Human iNKT Cell Autoreactivity via the Hypervariable CDR3β Loop

  • Gediminas Matulis,

    Affiliation: Center for Experimental Rheumatology, University of Bern, Inselspital, Bern, Switzerland

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  • Joseph P. Sanderson,

    Affiliation: Division of Infection, Inflammation and Immunity, University of Southampton, School of Medicine, Sir Henry Wellcome and “Hope” Laboratories, United Kingdom

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  • Nikolai M. Lissin,

    Affiliation: Immunocore Ltd., Abingdon, United Kingdom

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  • Maria B. Asparuhova,

    Affiliation: Institute of Cell Biology, University of Bern, Bern, Switzerland

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  • Gopal R. Bommineni,

    Affiliation: Fachbereich Chemie, University of Konstanz, Konstanz, Germany

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  • Daniel Schümperli,

    Affiliation: Institute of Cell Biology, University of Bern, Bern, Switzerland

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  • Richard R. Schmidt,

    Affiliation: Fachbereich Chemie, University of Konstanz, Konstanz, Germany

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  • Peter M. Villiger,

    Affiliation: Center for Experimental Rheumatology, University of Bern, Inselspital, Bern, Switzerland

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  • Bent K. Jakobsen,

    Affiliation: Immunocore Ltd., Abingdon, United Kingdom

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  • Stephan D. Gadola mail

    s.gadola@soton.ac.uk

    Affiliations: Center for Experimental Rheumatology, University of Bern, Inselspital, Bern, Switzerland, Division of Infection, Inflammation and Immunity, University of Southampton, School of Medicine, Sir Henry Wellcome and “Hope” Laboratories, United Kingdom

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  • Published: June 22, 2010
  • DOI: 10.1371/journal.pbio.1000402

Reader Comments (1)

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Which glycosylceramide have been used

Posted by Hellgren on 11 Feb 2011 at 09:54 GMT

It is very interesting data, but it would be very helpful if the authors stated whether it is beta-galactosylceramide or beta-glucosylceramide that have been used in this study.

Lars Hellgren
DTU Systems Biology

No competing interests declared.