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Research Article

A Map of Recent Positive Selection in the Human Genome

  • Benjamin F Voight equal contributor,

    equal contributor Contributed equally to this work with: Benjamin F Voight, Sridhar Kudaravalli

    Affiliation: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

    X
  • Sridhar Kudaravalli equal contributor,

    equal contributor Contributed equally to this work with: Benjamin F Voight, Sridhar Kudaravalli

    Affiliation: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

    X
  • Xiaoquan Wen,

    Affiliation: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

    X
  • Jonathan K Pritchard mail

    To whom correspondence should be addressed. E-mail: pritch@uchicago.edu

    Affiliation: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

    X
  • Published: March 07, 2006
  • DOI: 10.1371/journal.pbio.0040072

Reader Comments (2)

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Robust to bottlenecks

Posted by ecoronap on 05 Feb 2010 at 06:05 GMT

The demographic models included a variety of bottleneck models for East Asians and Europeans, and models of constant size with recent growth for Yoruba
http://plosbiology.org/article/info:doi/10.1371/journal.pbio.0040072#article1.body1.sec2.sec1.p3

I'm curious as to how robust this method is to bottleneck effects. I've looked at the main article and supplementary materials and didn't find a direct answer.

No competing interests declared.