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Research Article

Darwinian Evolution on a Chip

  • Brian M Paegel,

    Affiliations: Departments of Chemistry and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Gerald F Joyce mail

    To whom correspondence should be addressed. E-mail: gjoyce@scripps.edu

    Affiliations: Departments of Chemistry and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Published: April 08, 2008
  • DOI: 10.1371/journal.pbio.0060085

Reader Comments (1)

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Stimulating research indeed!

Posted by plosbiology on 07 May 2009 at 22:23 GMT

Author: Amit Mandal
Position: Graduate student
Institution: IGIB, Delhi
E-mail: ak.mandal@igib.res.in
Submitted Date: April 09, 2008
Published Date: April 9, 2008
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

I can very well perceive the enthusiasm of the authors to note evolution in real time. This reminds me of my college years as a Zoology grad when we did a simple Drosophila experiment to observe natural selection in a population. That is over a period of 4-6 weeks we observed how white-eyed flies dwindled out, from an initial population of equi-numbered white and red ones, due to selection during mating. So its really stimulating to 'see' variants of the RNA enzyme being 'selected' in response to changing 'environmental conditions' in real time.
Kudos to Paegel and Joyce!

No competing interests declared.