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Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

  • Carol Kilkenny mail,

    Affiliation: The National Centre for the Replacement, Refinement and Reduction of Animals in Research, London, United Kingdom

  • William J. Browne,

    Affiliation: School of Veterinary Science, University of Bristol, Bristol, United Kingdom

  • Innes C. Cuthill,

    Affiliation: School of Biological Sciences, University of Bristol, Bristol, United Kingdom

  • Michael Emerson,

    Affiliation: National Heart and Lung Institute, Imperial College London, United Kingdom

  • Douglas G. Altman

    Affiliation: Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom

  • Published: June 29, 2010
  • DOI: 10.1371/journal.pbio.1000412
  • Featured in PLOS Collections

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Congratulations and an observation

Posted by JohnCW on 28 Jul 2010 at 10:41 GMT

Firstly many congratulations on these guidelines. They should increase the value of the peer-reviewed litereture, the value of anmal experiments, and the return on funders' financial investment. I hope they are widely adopted.

An observation: as with all guidelines (I would suggest) there is a need for common sense in marginal cases. For example Paul Lauterbur's Nobel prize-winning mouse study (1) would not be in compliance, and arguably should not need to be brought into complete compliance were it publihed today.

(1) Lauterbur PC (1974). "Magnetic resonance zeugmatography". Pure and Applied Chemistry 40: 149–157. doi:10.1351/pac197440010149.

No competing interests declared.