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- Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System
- Distinct DNA Exit and Packaging Portals in the Virus Acanthamoeba polyphaga mimivirus
- Topography of Thalamic Projections Requires Attractive and Repulsive Functions of Netrin-1 in the Ventral Telencephalon
- Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated
- Mapping the Genetic Architecture of Gene Expression in Human Liver
Most Viewed
- Why We Sleep: The Temporal Organization of Recovery
- The Case of Deborah Rice: Who Is the Environmental Protection Agency Protecting?
- Birds Do It, Bees Do It, but Candida albicans Does It Differently
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- The Challenge of Conserving Amphibian Megadiversity in Madagascar
Weekly Editors' Picks
The Case of Deborah Rice: Who is the Environmental Protection Agency Protecting?
Why did the EPA dismiss a highly respected neurotoxicologist as chair of its external review panel on the fire retardant deca? Pioneering lead researcher Herbert Needleman, MD, argues that the answer has little to do with science.
Birds Do It, Bees Do It, but Candida albicans Does It Differently
The opportunistic fungal pathogen Candida albicans has a cryptic parasexual mating cycle characterized by chromosome loss. New evidence shows that genetic recombination occurs during the mating cycle and requires the activity of Spo11, a protein necessary for meiotic recombination in other eukaryotes.
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Interesting Structures: Education and Outreach at the RCSB Protein Data Bank
The Research Collaboratory for Structural Bioinformatics Protein Data Bank is part of an international consortium that works not only to make the data describing the 3-D shape of biological macromolecules available worldwide, but also to increase their usefulness in science, medicine, and education.
The Challenge of Conserving Amphibian Megadiversity in Madagascar
Highly diverse and—so far—apparently untouched by emergent diseases, Malagasy frogs nevertheless are threatened by ongoing habitat destruction, making pro-active conservation actions especially important for preserving this unique, pre-decline, amphibian fauna.
Why We Sleep: The Temporal Organization of Recovery
Why we sleep seems like a simple question, yet it has baffled scientists for generations. Based on recent data, Emmanuel Mignot argues that the function of sleep is essentially a resilient form of cellular recovery, organized anatomically and temporally by natural evolution, that has taken on additional functions over time.
Polycomb Group Genes: Keeping Stem Cell Activity in Balance
Overexpression of Polycomb group genes is often associated with cancer development, whereas complete deletion results in loss of stem cell activity. New studies show that partial loss of function of Polycomb group genes enhances the activity of blood stem/progenitor cells.
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April 2008 Issue
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